PICO is an acronym used to describe the four elements of a compelling clinical research question:
P - Population/Problem: How would I describe the problem or a group of patients similar to mine?
I - Intervention: What main intervention, prognostic factor, or exposure am I considering?
C - Comparison: Is there an alternative to compare with the intervention?
O - Outcome: What do I hope to accomplish, measure, improve, or affect?
Fill in the blanks with information from your clinical scenario:
THERAPY
In_______________, what is the effect of ________________on _______________ compared with _________________?
Use: Randomized Controlled Trials (RCTs), meta-analyasis. Also: cohort studies, case-control studies, case series.
PREVENTION
For ___________ does the use of _________________ reduce the future risk of ____________ compared with ______________?
Use: Randomized Controlled Trials (RCTs), meta-analyasis. Also: prospective studies, cohort studies, case-control studies, case series.
DIAGNOSIS OR DIAGNOSTIC TEST
Are (Is) ________________ more accurate in diagnosing _______________ compared with ____________?
Use: Randomized Controlled Trials (RCTs). Also: cohort studies.
PROGNOSIS
Does ____________ influence ______________ in patients who have _____________?
Use: Cohort studies. Also: case-control studies, case series.
ETIOLOGY
Are ______________ who have _______________ at ______________ risk for/of ____________ compared with _____________ with/without______________?
Use: Randomized Controlled Trials (RCTs), meta-analyasis, cohort studies. Also: case-control studies, case series.
MEANING
How do _______________ diagnosed with _______________ perceive __________________?
Use: Qualitative studies.
Melnyk, B. M., & Fineout-Overholt, E. (2011). Evidence-based practice in nursing & healthcare: A guide to best practice. Philadelphia: Wolters Kluwer/Lippincott Williams & Wilkins.
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